If you're a fan of comfort food, this Mac and Cheese Meatloaf Casserole recipe is a dream come true! This dish combines the savory flavors of meatloaf with the creamy, cheesy goodness of macaroni and cheese, creating a hearty casserole that's sure to satisfy. Whether you’re making a weeknight dinner for the family or bringing a dish to a potluck, this recipe is bound to be a crowd-pleaser. Read on to discover all the steps, tips, and tricks to make this ultimate comfort food, and learn how to make it your own with variations and substitutions!
What is a Mac and Cheese Meatloaf Casserole?
Mac and Cheese Meatloaf Casserole is a fusion of two classic dishes: meatloaf and macaroni and cheese. This dish layers a rich meatloaf base with creamy, cheesy macaroni, then bakes it to golden perfection. The result is a savory, cheesy, and filling casserole that’s easy to prepare and even easier to devour. It’s the perfect recipe for those who can't decide between their love of pasta and their craving for a delicious meatloaf.
Ingredients List for the Meatloaf Layer
Before diving into the recipe, let's gather all the ingredients you’ll need for the meatloaf layer:
- 1 pound ground beef
- ½ pound ground pork (optional, for extra flavor)
- 1 medium onion, finely chopped
- ½ cup breadcrumbs (preferably seasoned)
- ¼ cup milk
- 1 large egg
- 2 tablespoons Worcestershire sauce
- ¼ cup ketchup
- 1 tablespoon Dijon mustard
- Salt and pepper, to taste
- 1 teaspoon garlic powder
- 1 teaspoon dried oregano
Ingredients List for the Mac and Cheese Layer
Now, let's move on to the ingredients you’ll need for the mac and cheese layer:
- 2 cups elbow macaroni
- 2 tablespoons butter
- 2 tablespoons all-purpose flour
- 2 cups milk
- 2 cups shredded cheddar cheese (plus more for topping)
- ½ cup shredded mozzarella cheese
- Salt and pepper, to taste
- ½ teaspoon paprika (optional for added flavor)
- ¼ teaspoon nutmeg (optional but adds a unique touch)
Substitutions and Variations
This Mac and Cheese Meatloaf Casserole recipe is highly adaptable, and there are plenty of ways to make it your own:
- Meat Substitutions: You can use ground turkey, chicken, or even a plant-based ground meat substitute to make the dish lighter or vegetarian-friendly.
- Cheese Variations: Feel free to mix up the cheeses. Gouda, Monterey Jack, or even Pepper Jack can add different flavors to your mac and cheese layer.
- Pasta Alternatives: Swap out the elbow macaroni for other pasta shapes like rotini, penne, or shell pasta for a different texture.
- Vegetable Add-Ins: Add some finely chopped veggies like bell peppers, spinach, or mushrooms into the meatloaf mixture for added nutrition.
- Gluten-Free Option: Use gluten-free breadcrumbs in the meatloaf and gluten-free pasta for those who are sensitive to gluten.
Step-by-Step Cooking Instructions

Let's break down the process into easy-to-follow steps to ensure your Mac and Cheese Meatloaf Casserole comes out perfectly every time.
Step 1: Preheat the Oven
- Preheat your oven to 375°F (190°C). Grease a 9x13-inch baking dish lightly with cooking spray.
Step 2: Prepare the Meatloaf Layer
- In a large mixing bowl, combine the ground beef, ground pork, chopped onion, breadcrumbs, milk, egg, Worcestershire sauce, ketchup, mustard, salt, pepper, garlic powder, and oregano.
- Mix well using your hands or a spatula until all the ingredients are evenly incorporated.
- Press the meatloaf mixture evenly into the bottom of the prepared baking dish.
Step 3: Cook the Macaroni
- Cook the elbow macaroni in a large pot of salted boiling water according to the package instructions until al dente.
- Drain the pasta and set it aside.
Step 4: Make the Cheese Sauce
- In a medium saucepan, melt the butter over medium heat. Stir in the flour and cook for about 1-2 minutes to form a roux.
- Gradually add the milk, stirring constantly to avoid lumps, until the mixture thickens slightly.
- Remove the saucepan from the heat and stir in the cheddar cheese, mozzarella cheese, salt, pepper, paprika, and nutmeg until the cheese is completely melted and the sauce is smooth.
Step 5: Combine Mac and Cheese
- Stir the cooked macaroni into the cheese sauce until well-coated. Pour the macaroni and cheese mixture evenly over the meatloaf layer in the baking dish.
Step 6: Bake the Casserole
- Sprinkle some extra shredded cheddar cheese on top for a bubbly, golden crust. Bake in the preheated oven for 30-35 minutes, or until the top is golden brown and the casserole is heated through.
How to Cook Mac and Cheese Meatloaf Casserole: A Step-by-Step Guide
- Assemble the layers: Start with the meatloaf on the bottom of the dish, followed by the creamy macaroni and cheese.
- Bake until bubbly: Keep an eye on the casserole as it bakes to ensure the top turns a perfect golden brown without burning.
- Cool slightly before serving: Let the dish cool for about 5-10 minutes after baking so the layers set, making it easier to slice and serve.
Common Mistakes to Avoid
- Overmixing the Meatloaf: This can make the meatloaf tough. Mix just until the ingredients are combined.
- Not Seasoning the Macaroni Enough: Make sure to taste the cheese sauce and adjust seasoning before combining it with the pasta.
- Skipping the Roux Step: The roux is crucial for thickening the cheese sauce; don’t rush this step!
Serving and Presentation Tips
Mac and Cheese Meatloaf Casserole is a hearty dish that looks great with some simple garnishes and sides.
How to Serve Mac and Cheese Meatloaf Casserole
- Serve this dish hot with a simple side salad or steamed vegetables to balance the richness.
- For a homestyle touch, pair it with garlic bread or a soft dinner roll.
Presentation Ideas for Mac and Cheese Meatloaf Casserole
- Sprinkle chopped parsley or chives on top for a pop of color.
- Serve each portion with a small drizzle of hot sauce for those who enjoy a kick of heat.
- Use individual ramekins for a more elegant presentation if serving at a dinner party.
Mac and Cheese Meatloaf Casserole Recipe Tips
- Make Ahead: Prepare the meatloaf and cheese sauce layers separately the day before and assemble just before baking.
- Freezing: This casserole freezes well. Store in an airtight container and freeze for up to 3 months. Thaw overnight in the refrigerator before reheating.
- Leftovers: Store leftovers in the refrigerator in an airtight container for up to 4 days. Reheat in the oven at 350°F (175°C) until warmed through.
Frequently Asked Questions (FAQs)
1. Can I make this casserole gluten-free?
Yes! Substitute gluten-free breadcrumbs and pasta to make this dish gluten-free.
2. What’s the best cheese to use for mac and cheese?
Sharp cheddar is a classic choice, but feel free to mix in mozzarella, gouda, or even parmesan for extra flavor.
3. Can I make this dish in advance?
Absolutely! You can assemble the casserole up to a day in advance and keep it in the fridge until you’re ready to bake.
4. How do I prevent the cheese from curdling in the sauce?
Be sure not to overheat the cheese sauce; keep the heat at medium and stir constantly to avoid curdling.
5. What are good side dishes for this casserole?
A fresh salad, garlic bread, or roasted vegetables all pair nicely with this hearty dish.
Conclusion
There you have it—the ultimate Mac and Cheese Meatloaf Casserole recipe! This dish is the perfect fusion of two classic comfort foods, bringing together the hearty flavors of meatloaf with the creamy delight of mac and cheese. It's a versatile recipe that you can customize to suit your taste and dietary needs. Give it a try, and don’t forget to experiment with the variations and tips mentioned in this guide. We hope you enjoy every delicious bite of this mouth-watering casserole! Happy cooking!
PrintMac and Cheese Meatloaf Casserole Recipe
This Mac and Cheese Meatloaf Casserole recipe combines the classic flavors of macaroni and cheese with savory meatloaf for a hearty, all-in-one comfort food dish. Perfect for family dinners or gatherings, this casserole will be a crowd-pleaser. With simple ingredients and easy preparation, this recipe is a must-try!
- Prep Time: 15 minutes
- Cook Time: 45 minutes
- Total Time: 1 hour
- Yield: 6 servings 1x
- Category: Main Course
- Method: Baking
- Cuisine: American
- Diet: Gluten Free
Ingredients
- 1 lb ground beef
- 1 cup breadcrumbs
- 1 egg
- ½ cup onion, finely chopped
- 2 cups cooked macaroni
- 2 cups shredded cheddar cheese
- ¼ cup milk
- ¼ cup ketchup
- Salt and pepper to taste
Instructions
- Preheat the oven to 350°F (175°C).
- In a bowl, mix the ground beef, breadcrumbs, egg, and onion. Season with salt and pepper.
- Press the meat mixture into the bottom of a baking dish to form a meatloaf layer.
- In a separate bowl, combine the cooked macaroni, shredded cheddar cheese, and milk.
- Spread the macaroni and cheese mixture evenly over the meatloaf layer.
- Drizzle ketchup over the top.
- Bake for 45 minutes or until the meatloaf is fully cooked and the cheese is bubbly.
- Let cool slightly before serving.
Notes
- For added flavor, you can mix in herbs like parsley or garlic powder into the meatloaf mixture.
- Use different cheese varieties like mozzarella or pepper jack for a unique taste.
Nutrition
- Serving Size: 1 slice
- Calories: 420
- Sugar: 6g
- Sodium: 780mg
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