There's nothing like slicing into a perfectly baked meatloaf only to reveal gooey, melted mozzarella cheese hidden inside. This Mozzarella Stuffed Meatloaf is a comfort food classic with a cheesy twist that's sure to impress both kids and adults alike.

The first time I made this dish, I was experimenting with ways to make meatloaf more exciting for my family. That molten mozzarella center quickly turned this into a favorite, and now it’s a regular request in our household. Let’s dive into what makes this meatloaf so special!

Why You’ll Love This Mozzarella Stuffed Meatloaf

Get ready to fall in love with this mouthwatering take on a traditional meatloaf. Packed with flavor and loaded with cheese, this recipe is anything but boring.

First, the cheese-stuffed center makes every slice a delightful surprise. As you cut into the meatloaf, the melted mozzarella oozes out, creating a visual and culinary wow factor.

It’s also surprisingly simple to make. With just a few extra steps, you can take a basic meatloaf and turn it into something extraordinary – no advanced cooking skills required!

This recipe is a one-pan wonder, making cleanup a breeze. Pair it with a side of mashed potatoes and steamed veggies for a wholesome, satisfying dinner that feels both special and comforting.

Finally, it’s incredibly customizable. Whether you like your meatloaf with an extra tangy glaze or want to sneak in some veggies, this recipe can easily adapt to your tastes and dietary needs.

Ingredients Notes

This Mozzarella Stuffed Meatloaf uses simple, pantry-friendly ingredients that come together to create bold flavors. Let’s take a closer look at the stars of the show.

Ground beef: I recommend using an 80/20 mix of ground beef for the best balance of flavor and moisture. You can substitute part of the beef with ground pork or turkey if you like.
Breadcrumbs: These help bind the meatloaf and keep it tender. Panko or Italian-seasoned breadcrumbs work beautifully here.
Eggs: Eggs are the glue that holds everything together. They also add richness to the meat mixture.
Mozzarella cheese: The star of the show! Use a block of mozzarella and cut it into logs for the best gooey center. Pre-shredded mozzarella will work but won’t create the same effect.
Ketchup and Worcestershire sauce: These add a tangy, savory depth to the meatloaf. Save some ketchup for the glaze!
Onion and garlic: Freshly minced onion and garlic provide a burst of flavor. If you’re short on time, garlic powder and onion powder are good substitutes.

You’ll also need a loaf pan to shape and bake the meatloaf. For an even crispier exterior, bake it free-form on a baking sheet lined with parchment paper.

How to Make This Mozzarella Stuffed Meatloaf

Creating this show-stopping meatloaf is easier than you think! Let’s break it down step by step.

1. Prepare the meat mixture

In a large mixing bowl, combine ground beef, breadcrumbs, eggs, minced onion, garlic, Worcestershire sauce, and a generous pinch of salt and pepper. Use your hands or a spoon to mix until everything is evenly incorporated – but don’t overwork the meat, or it could become tough.

2. Shape the loaf

On a sheet of parchment paper or a cutting board, flatten the meat mixture into a rectangular shape, about 1 inch thick. Place your mozzarella logs in the center of the rectangle, then carefully fold the edges of the meat over the cheese, fully encasing it. Seal any seams by pressing the meat together gently.

3. Bake the meatloaf

Transfer the stuffed loaf into a greased loaf pan or onto a baking sheet. Spread a layer of ketchup or your favorite glaze over the top for extra flavor and caramelization. Bake in a preheated 375°F (190°C) oven for 50–60 minutes, or until the internal temperature reaches 160°F (71°C).

4. Rest and serve

Let the meatloaf rest for 10 minutes before slicing. This helps the juices redistribute and prevents the cheese from spilling out too quickly. Slice and serve with your favorite sides for a hearty, satisfying meal.

Storage Options

This Mozzarella Stuffed Meatloaf stores beautifully, making it perfect for meal prep or leftovers.

Refrigerator: Store slices in an airtight container for up to 3 days. Reheat in the microwave or oven for a quick and easy lunch or dinner.
Freezer: Wrap individual portions in plastic wrap, then place them in a freezer-safe bag. Freeze for up to 3 months. Thaw overnight in the fridge before reheating.

To reheat, warm in a 350°F oven for 15–20 minutes or until heated through. This will help maintain the crispy edges and gooey center.

Variations and Substitutions

One of the best things about this recipe is its versatility. Here are a few ways to make it your own:

Different cheeses: Swap out the mozzarella for cheddar, gouda, or pepper jack for a fun twist on flavor.
Low-carb version: Use almond flour or crushed pork rinds instead of breadcrumbs to make this meatloaf keto-friendly.
Spicy kick: Add diced jalapeños or a sprinkle of red pepper flakes to the meat mixture for a little heat.
Veggie boost: Mix in finely grated zucchini or carrots to sneak some extra nutrients into the meatloaf.
Herb lovers: Add fresh parsley, thyme, or basil to the mixture for a burst of freshness.

No matter how you customize it, this Mozzarella Stuffed Meatloaf is sure to become a family favorite. Don’t be afraid to experiment and make it uniquely yours!

Enjoy this cheesy, comforting dish with those you love most – it’s the kind of meal that brings everyone to the table.